Activates genes responsible for collagen, elastin, and glycosaminoglycan production.
Counteracts multiple signs of skin aging at the genetic level.
Accelerates wound healing and reduces scar tissue formation.
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper tripeptide found in human plasma, saliva, and urine. It was first identified in the 1970s and has since become one of the most studied peptides in skin biology — with over 50 years of published research on its regenerative properties.
GHK-Cu acts as a master regulator of tissue remodeling. It activates over 4,000 genes involved in tissue repair, including upregulation of collagen I, III, and IV synthesis, elastin production, glycosaminoglycan formation, and growth factor expression. The copper ion is essential — it serves as a cofactor for lysyl oxidase, the enzyme that cross-links collagen and elastin fibers into functional networks. GHK-Cu also has potent anti-inflammatory and antioxidant properties, reducing tissue damage while accelerating repair.
4,000+
genes activated by GHK-Cu — making it one of the most broadly regenerative peptides known in skin science, with over 50 years of published research.
GHK-Cu skincare represents the frontier of anti-aging peptide science. This copper tripeptide activates over 4,000 genes involved in skin remodeling — making it the most broadly regenerative compound in our formulations. As a copper peptide serum, it drives collagen regeneration, elastin synthesis, and glycosaminoglycan production simultaneously. With over 50 years of published research confirming its GHK-Cu benefits, this wound healing peptide doesn’t just slow aging — it reverses structural decline at the genetic level. Paired with signal peptides for additional collagen stimulation, Squalane to keep the lipid matrix supple, and a Ceramide 3 foundation that seals the regenerated layers from above. Combined with Hyaluronic Acid for hydration and Panthenol for accelerated barrier repair. Explore the full formulation in The Serum CU on Amazon.
GHK-Cu is the most powerful regenerative peptide we could find — and that’s exactly why it needs Ceramide 3. Deep remodeling means nothing if the barrier above it can’t hold. GHK-Cu rebuilds the dermis; Ceramide 3 seals the epidermis. Together, they regenerate skin from its deepest structural layer to its outermost protective surface.