Choosing the right skincare ingredients matters more than any brand name or marketing claim. Every St.GABRIEL’s serum is built on pharmaceutical-grade skincare ingredients backed by peer-reviewed clinical research. We select each active for its proven efficacy, optimal concentration, and synergy with Ceramide 3 — the foundation of every formula in The Serum line.
Below you’ll find all 30 skincare ingredients we use, what each one does, and why we chose it. No fillers, no fragrance, no ingredients without a job.
A powerful skin-soothing compound that accelerates cell regeneration, promotes wound healing, and softens the outer layer of skin for a smoother, calmer complexion.
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Nature’s most trusted healer — rich in polysaccharides, vitamins, and enzymes that hydrate, soothe inflammation, and accelerate skin repair on contact.
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A gentle tyrosinase inhibitor that fades dark spots and hyperpigmentation without irritation — clinically proven to brighten and even skin tone over time.
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Packed with oleic acid, vitamins A and E, and plant sterols that deeply nourish skin, boost collagen production, and restore elasticity to aging or damaged skin.
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The plant-based retinol alternative — clinically shown to reduce wrinkles and improve firmness without the irritation, dryness, or sun sensitivity of retinoids.
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Vitamin B7 — essential for keratin production and fatty acid synthesis. Strengthens the skin barrier, supports cell renewal, and improves overall skin resilience.
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Derived from chamomile — a potent anti-inflammatory and skin-calming agent that reduces redness, accelerates healing, and enhances penetration of other actives.
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An ancient medicinal herb containing madecassoside and asiaticoside — proven to stimulate collagen synthesis, repair barriers, and calm chronic inflammation.
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The foundation of every St.GABRIEL’s formula. This essential skin-identical lipid rebuilds the barrier mortar between cells, locking moisture in and irritants out.
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Rich in chamazulene and apigenin — two compounds clinically shown to reduce inflammation, soothe irritated skin, and protect against oxidative stress.
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The structural protein responsible for skin firmness and elasticity. Topical collagen peptides signal your skin to increase its own collagen production from within.
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A naturally occurring tripeptide that activates over 4,000 genes involved in tissue remodeling — stimulating collagen, elastin, and glycosaminoglycan production.
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Most skincare brands list active skincare ingredients on their labels without disclosing concentrations. A serum with 0.1% niacinamide and one with 10% niacinamide both say “contains niacinamide” — but only one will actually change your skin.
At St.GABRIEL’s, every skincare ingredient is included at a concentration backed by clinical evidence. Our formulas start with Ceramide 3 to rebuild and protect your skin barrier, then layer targeted actives like Vitamin C (SAP), Niacinamide, Retinol, and Hyaluronic Acid on top.
The result: skincare ingredients that work together instead of competing — because a strong barrier makes every active more effective. Explore The Serum C+E to see how these ingredients come together in our first formula.
